CIPROFLOXACIN + METRONIDAZOLE BENZOATE + TERBINAFINE HCl + CLOBETASOL PROPIONATE CREAM

Therapeutic Indication

Mixed bacterial and fungal skin infections with inflammation

Infected dermatoses

Fungal infections associated with itching and redness

Secondary bacterial infection in inflammatory skin conditions

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CIPROFLOXACIN + METRONIDAZOLE BENZOATE + TERBINAFINE HCl + CLOBETASOL PROPIONATE

CREAM

This topical cream is a multi-action dermatological formulation containing antibacterial, antifungal, antiprotozoal, and anti-inflammatory agents for comprehensive management of mixed microbial skin infections associated with inflammation and itching. Ciprofloxacin Hydrochloride is a fluoroquinolone antibacterial agent effective against susceptible gram-positive and gram-negative bacteria. Metronidazole Benzoate provides activity against anaerobic microorganisms and helps reduce infection-associated inflammation. Terbinafine Hydrochloride is a broad-spectrum antifungal agent effective against dermatophytes and fungal pathogens. Clobetasol Propionate is a potent topical corticosteroid that helps relieve redness, swelling, itching, and irritation.

Speciality	Dermatology \| Antifungal & Antibacterial Therapy
Tags	Antifungal \| Antibacterial \| Anti-inflammatory \| Dermatology \| Skin Infection Care
Strength	Ciprofloxacin Hydrochloride IP – 1% w/w Metronidazole Benzoate IP – 1% w/w Terbinafine Hydrochloride IP – 1% w/w Clobetasol Propionate IP – 0.05% w/w
Packing Size	15 gm Tube

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Mechanism

Ciprofloxacin Hydrochloride
Inhibits bacterial DNA gyrase and topoisomerase IV, preventing bacterial DNA replication and growth.
Metronidazole Benzoate
Disrupts nucleic acid synthesis in anaerobic microorganisms leading to microbial cell death.
Terbinafine Hydrochloride
Inhibits squalene epoxidase enzyme, disrupting fungal cell membrane synthesis and causing fungal cell death.
Clobetasol Propionate
Suppresses inflammatory mediators and reduces itching, redness, and swelling.

Side Effects

Peeling
Dryness
Redness

Contraindication

Hypersensitivity to any component of the formulation
Viral skin infections (e.g., herpes simplex, chickenpox)
Rosacea
Open wounds unless advised by physician
Acne vulgaris
Tubercular or syphilitic skin lesions

Dosage

Use as directed by the physician

DRUG INTERACTIONS

Concurrent use with other topical corticosteroids may increase adverse effects
Occlusive dressings may enhance systemic absorption
Avoid simultaneous use with irritating topical products unless advised

Warning and Precautions

For external use only
Avoid contact with eyes, mouth, and mucous membranes
Do not apply on large body surface areas
Avoid prolonged use without medical supervision
Use cautiously in children and elderly patients
Discontinue use if severe irritation or hypersensitivity occurs
Do not cover treated area with airtight dressing unless prescribed
Store in a cool, dry place
Keep out of reach of children

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.